If you're new in the area, don't go to a new place by yourself. If you're out with a group of friends, stay together and make sure your friends know where you are.
No Thanks!
Don't accept drinks from anyone you don't trust or know. Although a free drink may seem like a cheap option at the time, you don't know what's in it. If you do accept a drink from a stranger, make sure you take it directly from the bar staff.
Plan Ahead
Before you leave, think about how you'll get home. Walking home by yourself at night could be dangerous. Also, think about who you accept lifts from. Check that any private mini-cab firm has a licence before you get in and ring for a mini-cab instead of accepting a lift from a crawler.